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Wednesday, August 5, 2020 | History

2 edition of Study of sound-produced seizure in the white rat. found in the catalog.

Study of sound-produced seizure in the white rat.

W. R. Thompson

Study of sound-produced seizure in the white rat.

by W. R. Thompson

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  • 13 Currently reading

Published .
Written in English


Edition Notes

Thesis (M.A.) -- University of Toronto, 1947.

The Physical Object
Pagination1 v.
ID Numbers
Open LibraryOL17295870M

Temporal lobe epilepsy (TLE) is a chronic disorder of the nervous system characterized by recurrent, unprovoked focal seizures that originate in the temporal lobe of the brain and last about one or two minutes. TLE is the most common form of epilepsy with focal seizures. A focal seizure in the temporal lobe may spread to other areas in the brain when it may become a focal to bilateral seizure. •Philipeaux studied adrenalectomized white rats in France in with •Rat pups are born ( g, affected by litter size), eyes will open at days and ears at days. They are hairless (fully haired days), and with no erupted teeth (incisor erupt at days). Anogenital space is used to differentiate newborns’.

  Rats -- better yet, frightened rats -- are the key, says Dr. Joseph LeDoux, a year-old neuroscientist at New York University who pioneered the study of emotions as biological phenomena.   My 17 year old daughter had a seizure event on April 1. We witnessed the first tonic-clonic (grand mal) seizure at home and then she had a second one in the ER about an hour later. We, along with her neurologist, suspect she may have had one .

neocortical partial seizure were used in this study. Rats of each model were randomly allocated into two groups: control and model groups. The model group was further divided into the KA or penicillin group, sham conduction group and conduction group. The current shunt was realized through the implantation of a customized conduction electrode. b) By removing the precise brain location where epileptic seizures originated, the seizures should stop. c) By selectively removing portions of the left hemisphere, language functions should shift to the right hemisphere. d) By cutting the corpus callosum, seizure activity should be contained in just one hemisphere of the brain.


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Study of sound-produced seizure in the white rat by W. R. Thompson Download PDF EPUB FB2

In this experimental study, 64 male rats were used. Kindling seizures were induced by three injections of 25 mg/kg of PTZ every 15 min. Control animals received normal saline instead. To evaluate the therapeutic effect of Boswellia extract on the PTZ-induced cognitive deficits, the aqueous extract (0,or 1 g/kg, i.p.) were Cited by: Fig.

1A describes the timing of mannitol, methotrexate arterial infusion, blood sampling for Sβ measurement, CT scan, and probability of seizure onset (red-to-white triangle). Note that S β serum levels were always assessed immediately after BBBD with mannitol (5′, dotted box in Fig.

1A) and before the onset on focal motor seizures Cited by: OBJECTIVE. Chronic seizures in women can have adverse effects on reproductive function, such as polycystic ovarian syndrome (PCOS), but it has been difficult to dissociate the effects of epilepsy per se from the role of antiepileptic drugs (AEDs).

To distinguish the effects of chronic seizures from AEDs, we used the laboratory rat, where an epileptic condition can be induced without Cited by: A.

Obenaus, E.J. Kendall, in Encyclopedia of Basic Epilepsy Research, Animal Models of Epilepsy. Rat models are widely used by experimental epileptologists. Partial seizures (arising from a restricted brain regions) can be induced by topical or regional application of amino acids antagonists (e.g., penicillin, bicuculline) or excitatory amino acid agonists (e.g., kainic acid); systemic.

Although our study shows a lack of effect of octanoic acid in seizure control, and this is supported by others (Brill et al., ; Hou et al., ; Liu and Pollack, ; Loscher and Nau, ), a recent study has shown octanoic acid increases threshold in the PTZ and 6-HZ seizure Cited by:   Rats are less likely to assist a fellow rodent in need if other members of their group are being unhelpful, according to a study that sheds new light on the so-called “bystander effect.” Peggy.

Models of Seizures and Epilepsy is a valuable, practical reference for investigators who are searching for the most appropriate laboratory models for addressing key questions in the field.

It also provides an important background for physicians, fellows, and students, offering insight into the potential for advances in epilepsy research. Re: Weird sounds before a Seizure, And auras without Seizures Submitted by Harrie on Wed, I used to have Bad seizures at night when I had just gone to.

Just about anything can trigger a can even have a seizure without triggers.I do all the worst triggers are heat&humidity andI also have photo sensitive seizures brought on by my tv and can doit to sleep Ican just go into a seizure.

Books at Amazon. The Books homepage helps you explore Earth's Biggest Bookstore without ever leaving the comfort of your couch. Here you'll find current best sellers in books, new releases in books, deals in books, Kindle eBooks, Audible audiobooks, and so much more. One study showed increased T2 signal two weeks after rat amygdala-kindled seizures without status epilepticus, but no difference in hippocampal volumes.

The value of MRI for prediction of neuronal injury in experimental seizure models is uncertain. In the present study, we established a transgenic rat strain harboring a human ADNFLE mutation of the β2-subunit of nAChR (VL-TG). VL-TG rats developed spontaneous epileptic seizures and a hypersensitivity to nicotine administration.

The seizures in these transgenic rats are similar to “paroxysmal arousals” of ADNFLE patients. In book: Models of Seizures and Epilepsy, pp In this study postnatal day (PND) 14, 21 and 28 rat pups, along with PND70 animals as adult controls, were exposed to NAs (sarin, VX) or.

From sixteen years old to forty eight years old, I have had seizures ranging from A sense seizures to Grand Map seizures. I don't recall making any noises except for nearly pulling a screen door off until my grip slipped and a grand mal commenced. I'm relatively new to seizures - diagnosed less than 2 years ago.

My seizures come from my language center, as my symptoms are always language related. I've found out that certain words/short phrases would trigger my simple partial seizure (unable to speak and understanding speech/printed words).

These practices increase the chance that data regarding an increase in IS in seizure prone rats is inflated due to the presence of a seizure artifact.

Limitations of this study. A limitation of this study was that the WAG/Rij rat the literature refers to was not used in this study. Instead, a different strain of seizure prone rat was used. For Ben, the rat who had the most seizures to start (about 7 per day), the medication reduced this to grand mal seizures a day plus numerous petit mal seizures.

Dohner wrote a prescription so Robbie could buy tablets at a time from Walgreens so she could buy them at a reasonable price. Observing that severe brain seizures called status epilepticus triggered the production of estrogen in the hippocampus of rats, the investigators determined that drugs that blocked estrogen.

The heritability of audiogenic seizure in rats was no less simple issue. In KM rats the diallelic cross showed that AE heritability is polygenic with additive effects, and alleles determining the resistance to sound induced seizures were dominant (Romanova et al., ).

The data on the genetic experiments in other AE rat strains are the following. Objective: To study the long-term effect of early seizures on later seizure-induced neuronal damage and behavior. Methods: We used a “two hit” rat seizure mode in which systemic kainate was used to induce seizures during the second week of life (P15) and again in adulthood (P45).

Memory was subsequently tested using a Morris water maze, and. ECS is a good idea which we regularly do to induce seizure in mice.

The only thing is you have to standardise the pulse. We standardised for adult C57 male mice and use the shock pulse machine of.Bursts of High-frequency Repetitive Transcranial Magnetic Stimulation (rTMS), Together with Lorazepam, Suppress Seizures in a Rat Kainate Status Epilepticus Model Becoming Comfortable with "My" Epilepsy: Strategies that Patients Use in the Journey from Diagnosis to Acceptance and Disclosure.Mark S.

LeDoux, in Movement Disorders (Second Edition), Haloperidol. Catalepsy is a condition characterized by lack of response to external stimuli and muscular rigidity; the limbs remain in whatever position they are placed. Neuroleptic drugs can induce catalepsy. The bar test was used to measure the cataleptic response to haloperidol in dystonic rats and normal littermates at.